書誌事項
- タイトル別名
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- Biomaterial Fabrication by Glycoconjugates
- トウサ シュウセキカ ニ ヨル バイオマテリアル ノ カイハツ
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抄録
The saccharides on the cell surfaces have the bio-signals in the life phenomena, and the biomaterials with molecular recognition abilities were fabricated based on the saccharide. The bio-materials with large molecular recognition abilities were fabricated by the saccharide assembly, which amplified the molecular recognition abilities by the multivalency. The glyco-conjugates with thin layer, nanoparticles and polymers were designed. The glyco-conjugates had the optical and electrochemical functionalities, which were used for the biosensing of proteins and pathogens. We have prepared the glyco-thin layer, which could detect Shiga toxins and amyloid beta peptides. We also prepared the glyco-substrates and glyco-nanoparticles via RAFT living radical polymerization, which showed the high specificity to proteins. Moreover, the glyco-dendrimer with dendrimer showed that the glyco-conjugate could control the protein amyloidosis and cytotoxicity.
収録刊行物
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- 粉体工学会誌
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粉体工学会誌 48 (3), 124-131, 2011
一般社団法人 粉体工学会
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詳細情報 詳細情報について
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- CRID
- 1390001204512673280
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- NII論文ID
- 10027915861
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- NII書誌ID
- AN00222757
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- ISSN
- 18837239
- 03866157
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- NDL書誌ID
- 11042051
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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- 抄録ライセンスフラグ
- 使用不可