幹細胞の機能を制御する高分子表面グラフト化材料

書誌事項

タイトル別名
  • Polymer-Grafted Surfaces for the Manipulation of Stem Cell Functions
  • カンサイボウ ノ キノウ オ セイギョ スル コウブンシ ヒョウメン グラフトカ ザイリョウ

この論文をさがす

抄録

The surface properties of biomaterials, including chemical composition, nano- or microstructured morphology, wettability, elasticity and electrostatic property, are very important for manipulation of stem cell functions such as adhesion, proliferation and differentiation. Photoreactive polyallylamine, poly (acrylic acid), poly (ethylene glycol) and poly (vinyl alcohol) were grafted or micro-patterned onto cell culture polystyrene plates by UV irradiation. Human mesenchymal stem cells (MSC), a promising cell source for regenerative medicine were cultured on the polymer-grafted or micropatterned plates to investigate the effect of functional groups on their chondrogenic, osteogenic, and adipogenic differentiation. The adhesion, proliferation, and differentiation of MSC could be manipulated by the polymer-grafted or micropatterned surfaces.

収録刊行物

  • 粉体工学会誌

    粉体工学会誌 48 (3), 132-139, 2011

    一般社団法人 粉体工学会

参考文献 (37)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ