NOS Activity in Mutant Rodents Susceptible for Epilepsy or Convulsions.

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  • てんかん性ミュータント動物における神経型の一酸化窒素合成酵素(NOS)活性

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Abstract

The relationship between NOS (nitric oxide Synthase) activity and the susceptibility to epilepsy/convulsion was investigated in the brain of Mongolian gerbils and Sprague-Dawley rats. The NOS activity in the seizure sensitive group of Mongolian gerbils is significantly lower than that in the seizure resistant group.<BR>The NOS activity and the susceptibility to epilepsy/convulsion were inversely correlated.

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