A Study on Interictal and Postictal Headaches in Patients with Epilepsy

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  • てんかんにおける発作間欠時頭痛および発作後頭痛の検討

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We investigated characteristics of headaches, both independent of seizures (interictal headaches, IH) and following seizures (postictal headaches, PH) in patients with epilepsy. Two hundred and seventy-five patients were questioned by epileptologists using a questionnaire. IH occurred in 49% of the patients. The frequency of IH monthly in 42% and yearly in 29%. They were found to be steady in 47% with pounding occurring in 44%. Degree of severity was mild in 59%. Accompanying symptoms were seen in 25%. Female and younger patients and those with a family history of headaches were significantly more common among those with IH than those without. Other clinical features showed no differences between these two groups. PH occurred in 35% of the patients. In 67%, PH occurred always or often following seizures. They were found to be steady in 54%, with a mild degree of severity was in 42% and severe in 26%.Accompanying symptoms were seen in 35%. PH were more likely to be associated with generalized tonic-clonic seizures. Other clinical features showed no difference between patients with PH and patients without. These findings are inconsistent with previous reports that both IH and PH have migrainous characteristics. Clinical analyses suggest that IH may be related to a genetic susceptibility to headaches and that PH may be related to seizures.

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