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Ototoxicity and bacteriostatic activity of various solutions used in the middle ear cavity for irrigation
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- YAMANO Takafumi
- Department of Otorhinolaryngology, Chikushi Hospital Fukuoka University Department of Otolaryngology, School of Medicine, Fukuoka University
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- SUGAMURA Mayumi
- Department of Otolaryngology, School of Medicine, Fukuoka University
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- HIGUCHI Hitomi
- Department of Otolaryngology, School of Medicine, Fukuoka University
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- UENO Tetsuko
- Department of Otolaryngology, School of Medicine, Fukuoka University
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- NAKAGAWA Takashi
- Department of Otolaryngology, School of Medicine, Fukuoka University
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- MORIZONO Tetsuo
- Nishi-Fukuoka Hospital
Bibliographic Information
- Other Title
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- 点耳薬剤の内耳毒性と MRSA に対する殺菌効果に対する実験的研究
- − ブロー液、ポビドンヨード、強酸水の比較 −
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Description
The ototoxicity and bacteriostatic activity of three different solutions, Burow's solution, Povidone-Iodine (ISODINE) solution and electrolyzed strong solution (ESAS), were studied in guinea pigs. Ototoxicity was evaluated using the eighth nerve compound action potential (CAP) measured using round window electrodes. The bacteriostatic activity was evaluated by measuring the diameter of the bacteriostatic ring of an agar plate containing MRSA. Bacteriostatic activity was noted in both Burow's solution and 1/5-strength Povidone-Iodine (ISODINE) solution. Full-strength Povidone-Iodine solution showed no ototoxic effects, unlike Burow's solution. ESAS exhibited no bacteriostatic activity or ototoxic effects.
Journal
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- jibi to rinsho
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jibi to rinsho 59 (4), 162-166, 2013-07-20
JIBI TO RINSHO KAI
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Details 詳細情報について
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- CRID
- 1390001204572427392
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- NII Article ID
- 130004679822
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- ISSN
- 21851034
- 04477227
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed