Ototoxicity and bacteriostatic activity of various solutions used in the middle ear cavity for irrigation

DOI
  • YAMANO Takafumi
    Department of Otorhinolaryngology, Chikushi Hospital Fukuoka University Department of Otolaryngology, School of Medicine, Fukuoka University
  • SUGAMURA Mayumi
    Department of Otolaryngology, School of Medicine, Fukuoka University
  • HIGUCHI Hitomi
    Department of Otolaryngology, School of Medicine, Fukuoka University
  • UENO Tetsuko
    Department of Otolaryngology, School of Medicine, Fukuoka University
  • NAKAGAWA Takashi
    Department of Otolaryngology, School of Medicine, Fukuoka University
  • MORIZONO Tetsuo
    Nishi-Fukuoka Hospital

Bibliographic Information

Other Title
  • 点耳薬剤の内耳毒性と MRSA に対する殺菌効果に対する実験的研究
  • − ブロー液、ポビドンヨード、強酸水の比較 −

Search this article

Description

The ototoxicity and bacteriostatic activity of three different solutions, Burow's solution, Povidone-Iodine (ISODINE) solution and electrolyzed strong solution (ESAS), were studied in guinea pigs. Ototoxicity was evaluated using the eighth nerve compound action potential (CAP) measured using round window electrodes. The bacteriostatic activity was evaluated by measuring the diameter of the bacteriostatic ring of an agar plate containing MRSA. Bacteriostatic activity was noted in both Burow's solution and 1/5-strength Povidone-Iodine (ISODINE) solution. Full-strength Povidone-Iodine solution showed no ototoxic effects, unlike Burow's solution. ESAS exhibited no bacteriostatic activity or ototoxic effects.

Journal

  • jibi to rinsho

    jibi to rinsho 59 (4), 162-166, 2013-07-20

    JIBI TO RINSHO KAI

Keywords

Details 詳細情報について

  • CRID
    1390001204572427392
  • NII Article ID
    130004679822
  • DOI
    10.11334/jibi.59.162
  • ISSN
    21851034
    04477227
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

Report a problem

Back to top