PROTECTION OF IMIDE GROUP OF URACIL MOIETY BY MEANS OF 2,2,2-TRICHLORO-<I>TERT</I>-BUTYLOXYCARBONYL CHLORIDE: A SELECTIVE SYNTHESIS OF 2′-<I>O</I>-METHYLURIDINE

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  • ChemInform Abstract: PROTECTION OF IMIDE GROUP OF URACIL MOIETY BY MEANS OF 2,2,2‐TRICHLORO‐TERT‐BUTYLOXYCARBONYL CHLORIDE: A SELECTIVE SYNTHESIS OF 2′‐O‐METHYLURIDINE

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2,2,2-Trichloro-tert-butyloxycarbonyl group (TCBOC) was useful protecting group for the protection of imide function of uracil moiety. Starting from N3-TCBOC uridine derivative, 2′-O-methyluridine was selectively synthesized without formation of N3-methyluridine derivatives.

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  • Chemistry Letters

    Chemistry Letters 11 (7), 965-968, 1982-07-05

    The Chemical Society of Japan

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