<i>Staphylococcus aureus</i> Detection by Fluorescent Silica Nanoparticles Modified with Metal–Dipicolylamine Complexes

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  • Kasai Yuna
    Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University
  • Kobayashi Hiroyuki
    Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University
  • Tsuchido Yuji
    Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University
  • Hashimoto Takeshi
    Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University
  • Kanzawa Nobuyuki
    Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University
  • Hayashita Takashi
    Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University

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Other Title
  • Staphylococcus aureus detection by fluorescent silica nanoparticles modified with metal-dipicolylamine complexes

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Description

We have developed a new method for Staphylococcus aureus (S. aureus) detection, which employs fluorescent silica nanoparticles (FSiNPs) modified with metal–dipicolylamine complex (M-dpa-HCC). Among the M-dpa-HCC/FSiNP complexes, Cu-dpa-HCC/FSiNP formed large aggregates with S. aureus in 10 min, which were easily observed by the naked eye. The antibacterial activity of Cu-dpa-HCC/FSiNP was also confirmed.

Journal

  • Chemistry Letters

    Chemistry Letters 45 (7), 749-751, 2016

    The Chemical Society of Japan

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