A Case Report of Severe Chronic Periodontitis Evaluated by Serum IgG Antibody Titer Test against Periodontal Pathogens

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  • Naruishi Koji
    Division of Periodontology, Department of Conservative Dentistry Iwate Medical University
  • Kunimatsu Kazushi
    Division of Periodontology, Department of Oral Rehabilitation, Iwate Medical University

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  • 重度歯周病患者における歯周病原性細菌に対する血清IgG抗体価の変化:症例報告

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Abstract

Chronic periodontitis is a polymicrobial infectious disease which may result in loss of teeth by inflammation-mediated bone resorption. More than 500 individual cultivable species of microbes have been identified in the human mouth, and the microbiological examinations for periodontitis have been available to dental clinicians since the late 1980s. Infection with periodontal pathogens leads to humoral immunological responses and elevates the levels of serum IgG antibody to the antigens. Since serum IgG antibodies levels correspond to the amount of periodontal bacteria, the effects of treatments focused on elimination of bacteria could be evaluated by decrease of serum IgG titer to the pathogens. In the present case report, we propose the clinical usefulness of serum IgG antibody levels as a marker for periodontal treatment effects.

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