書誌事項
- タイトル別名
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- Effects of inflammatory chemical mediators on porcine lingual arterial smooth muscle
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抄録
To elucidate the effects of various chemical mediators, which are considered to appear in inflammation, on vascular smooth muscle, annular specimens of porcine lingual arterial smooth muscle were prepared, and divided into specimens denuded or undenuded of vascular endothelium. These specimens were attached to the thermostat incubator of an intracellular calcium ion concentration measurement unit, stimulated with 40 mM KCl, noradrenalin (NA), or U46619, followed by administration of acetylcholine (ACh) or bradykinin (BK), and the isometric contractile tension generated and fluorescence intensity ratio were simultaneously measured ; the following conclusions were drawn. 1. The inhibition by ACh or BK of NA-, high KCl-, or U46619-induced contraction was dependent on the presence of vascular endothelium, suggesting the involvement of a decreased [Ca^<2+>]_i concentration in the contraction inhibition. 2. It was suggested that the inhibition of high KCl-induced contraction by ACh or BK was weaker than that of receptor stimulation-induced contraction. 3. The administration of BK showed biphasic changes in U46619-induced contractile tension and [Ca^<2+>]_i.
収録刊行物
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- 岩手医科大学歯学雑誌
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岩手医科大学歯学雑誌 32 (2), 149-150, 2007
岩手医科大学歯学会
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詳細情報 詳細情報について
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- CRID
- 1390001204590328064
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- NII論文ID
- 110006368270
- 110006249451
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- NII書誌ID
- AN00017474
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- ISSN
- 24241822
- 03851311
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- IRDB
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可