Study on the Components of Luobuma with Peroxynitrite-Scavenging Activity
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- Yokozawa Takako
- Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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- Kashiwada Yoshiki
- Niigata College of Pharmacy
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- Hattori Masao
- Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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- Chung Hae Young
- College of Pharmacy, Pusan National University
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説明
The origin of the antioxidant activity of Luobuma aqueous extract was examined by measuring the peroxynitrite (ONOO−)-eliminating activities of fractions of this extract obtained by Sephadex LH-20 column chromatography. Three of the four fractions obtained, i.e., those excluding the H2O-eluted fraction, were found to possess ONOO−-eliminating activity. These three fractions were combined and fractionated again by Sephadex LH-20 column chromatography, which yielded five fractions. Seven different compounds were isolated from two of these five fractions with high activity. Epigallocatechin-(4β-8)-epicatechin showed the highest ONOO−-eliminating activity.
収録刊行物
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- Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ
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Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ 25 (6), 748-752, 2002
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204628292352
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- NII論文ID
- 110003638751
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- NII書誌ID
- AA10885497
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- COI
- 1:CAS:528:DC%2BD38XkvV2gsro%3D
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- ISSN
- 13475215
- 09186158
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- NDL書誌ID
- 6175023
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- PubMed
- 12081141
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- 本文言語コード
- en
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- データソース種別
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- NDLサーチ
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- PubMed
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- 使用不可