Recent Advances in the Study on Resveratrol
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- Nakata Rieko
- Department of Food Science and Nutrition, Nara Women's University
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- Takahashi Satoru
- Department of Immunobiology, School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women's University
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- Inoue Hiroyasu
- Department of Food Science and Nutrition, Nara Women's University
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Abstract
Appropriate long-term drinking of red wine is associated with a reduced risk for lifestyle-related diseases such as cardiovascular disease and cancer, making resveratrol, a constituent of grapes and various other plants, an attractive compound to be studied. Historically, resveratrol has been identified as a phytoalexin, antioxidant, cyclooxygenase (COX) inhibitor, peroxisome proliferator-activated receptor (PPAR) activator, endothelial nitric oxide synthase (eNOS) inducer, silent mating type information regulation 2 homolog 1 (SIRT1) activator, and more. Despite scepticism concerning the biological availability of resveratrol, a growing body of in vivo evidence indicates that resveratrol has protective effects in several stress and disease models. Here, we provide a review of the studies on resveratrol, especially with respect to COX, PPAR, and eNOS activities, and discuss its potential for promoting human health.
Journal
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- Biological and Pharmaceutical Bulletin
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Biological and Pharmaceutical Bulletin 35 (3), 273-279, 2012
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390001204631566976
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- NII Article ID
- 130001872306
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- NII Book ID
- AA10885497
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- COI
- 1:STN:280:DC%2BC383nvVWhsg%3D%3D
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- ISSN
- 13475215
- 09186158
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- NDL BIB ID
- 023439510
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- PubMed
- 22382311
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed