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Impulse Oscillometry; Therapeutic Impacts of Transdermal Long-Acting Beta-2 Agonist Patch in Elderly Asthma with Inhaled Corticosteroid Alone
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- Tanaka Hiroshi
- Sapporo Cough Asthma and Allergy Center Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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- Hozawa Soichiro
- Hiroshima Allergy and Respiratory Clinic
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- Kitada Junya
- Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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- Fujii Masaru
- Third Department of Internal Medicine, Sapporo Medical University School of Medicine
Bibliographic Information
- Other Title
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- Impulse oscillometry:therapeutic impacts of transdermal long-actinb P2 agonist patch in elderly asthma with inhaled corticosteroid alone
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Description
Growing interest had been focused on the involvement of the small airways in asthma, and impulse oscillometry (IOS) has been utilized as pulmonary functions for detecting large and small airways diseases separately. IOS can measure respiratory resistance and reactance at multiple frequencies, not available by spirometry or body plethysmography, is non-invasive techniques and convenient for elderly patients with a low dependency on cooperation during tidal breathing. IOS indices were well correlated with not only predicted FEV1 but also FEF25-75, residual volume/total lung capacity, delta N2 of a single nitrogen washout test which representing air trapping and inhomogeneous ventilation in the distal lung. These parameters and QOL scores were improved by additional transdermal long-acting beta-2 agonist patch even in well-controlled elderly asthma treating with inhaled corticosteoids alone. IOS may have a complementary role of spirometry in detecting subtle airways changes in general practice. However, systemic studies are required to investigate the clinical implication of each IOS index.<br>
Journal
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- Allergology International
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Allergology International 61 (3), 385-392, 2012
Japanese Society of Allergology
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Keywords
Details 詳細情報について
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- CRID
- 1390001204633132032
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- NII Article ID
- 130004477161
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- COI
- 1:CAS:528:DC%2BC38XhsVKlsbrO
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- ISSN
- 14401592
- 13238930
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- PubMed
- 22824980
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed
