ラクナ梗塞の発症時間と高血圧，糖尿病および降圧薬の影響

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  • Effect of hypertension, diabetes mellitus and antihypertensives on onset time in cases of lacunar stroke.

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We investigated the effects of hypertension, diabetes mellitus, and antihypertensives on the onset time of lacunar stroke (n=246). There were peaks of high incidence of stroke during sleeping at night and during activity in the afternoon. In patients with hypertension alone, stroke onset was frequent during sleeping at night in cases under treatment with antihypertensives and during activity in the afternoon in cases receiving no antihypertensives. These findings suggest that stroke may occur in patients whose blood pressure is decreased by antihypertensives at night and in patients whose blood pressure is increased by activity in the afternoon. In patients with both hypertension and diabetes mellitus, stroke onset in cases under treatment with antihypertensives was frequent not only during nighttime sleeping but also during afternoon activity. This implies that diabetes mellitus may impair autoregulation of blood pressure.

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  • 脳卒中

    脳卒中 23 (2), 208-210, 2001

    一般社団法人 日本脳卒中学会

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