Long-term outcome of acute pancreatitis

DOI Web Site 1 Citations 17 References
  • UEDA Takashi
    Department of Gastroenterological Surgery, Kobe University Graduate School of Medical Sciences
  • KURODA Yoshikazu
    Department of Gastroenterological Surgery, Kobe University Graduate School of Medical Sciences
  • TAKEYAMA Yoshifumi
    Department of Surgery, Kinki University School of Medicine
  • 安田 武生
    神戸大学大学院医学系研究科消化器外科学
  • 松村 直樹
    神戸大学大学院医学系研究科消化器外科学
  • 沢 秀博
    神戸大学大学院医学系研究科消化器外科学
  • 中島 高広
    神戸大学大学院医学系研究科消化器外科学
  • 阪上 順一
    京都府立医科大学大学院消化器病態制御学
  • KATAOKA Keisho
    Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science
  • KASHIMA Kei
    Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science
  • OTSUKI Makoto
    Third Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine

Bibliographic Information

Other Title
  • 急性すい炎の長期転帰

Description

We analyzed long-term outcome of acute pancreatitis (311 severe and 403 moderate cases, at 13-18 years after onset) from the data of national survey by the Intractable Diseases of the Pancreas, Japanese Ministry of Health, Labor and Welfare. The proportion of patients who continued to drink was 30.4%. Recurrence of acute pancreatitis was noted in 20.3%, and was high (20.3%) in alcoholic pancreatitis and low (7.4%) in gallstone pancreatitis. Recurrence rates of acute pancreatitis in the persistent drinkers and in patients with transition to chronic pancreatitis were high (57.7% and 74.5%, respectively). The transition to chronic pancreatitis was noted in 14.8%, and was high (26.0%) in alcoholic pancreatitis and low (1.7%) in gallstone pancreatitis. The transition rates to chronic pancreatitis in the persistent drinkers and in patients with more than twice recurrence of acute pancreatitis were high (40.9% and 61.4%, respectively). Complication with diabetes mellitus was noted in 13.0%, and the rate was high (20.6%) in alcoholic pancreatitis. The percentage of patients who developed diabetes mellitus among the persistent drinkers was high (37.2%). The mortality rate by malignancy was 6.0%. Our results indicate poor long-term outcome in alcoholic acute pancreatitis and persistent drinkers.

Journal

  • Suizo

    Suizo 20 (5), 455-464, 2005

    Japan Pancreas Society

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