Quantitative analysis of gait in patients with severe ischemic lesions in the white matter

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  • 大脳白質高度虚血病変例における定量的歩行評価

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Abstract

We quantitated the function of walking in 34 patients with severe ischemic lesions in the white matter, clarifying the association with other staging markers (intellectual function, orthostatic blood pressure change, and periventricular hyper-intensity on T2-weighted MRI). The necessary time to 10-meter walking showed an inverse correlation with the numbers on the Kana pick-up test, and the average steps per day was correlated with the Kana pick-up test data. The orthostatic blood pressure decline was more marked in patients who took under 5, 000 steps per day than in those taking over 5, 000 steps. Furthermore, an inverse correlation was noted between the average steps per day and the severity of periventricular hyperintensity. Gait disturbance is an important symptom of lesions of the white matter, so that analysis of gait, especially of the average steps per day, is thought to be useful as a quantitative marker of the severity of this condition.

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