脳梗塞急性期における血小板凝集能の男女差の検討

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  • Sex difference of platelet aggregation in patients with acute stage-cerebral infarction.

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Platelet aggregation (PA) was measured for 2 μM ADP in 130 patients with acute stage-cerebral infarction. In 86 of them, antithrombin III (AT III) and α2-plasmin inhibitor (APL) were also measured. They were classified by type and sex as follows : Lacunar group (L group), Atherothrombotic group (T group), Cardioembolic group (E group) and Male group (M group) and Female group (F group). The examinations were made in six groups of ML, MT, ME, FL, FT and FE. The control group comprizes ambulatory patients with some risk factors of arteriosclerosis. Compared with the controls, the patient group showed decreased PA, AT III and APL. Values of PA and AT III were lower in E group than in L and T groups, but there was no difference in APL. M group showed lower values than F group in PA, AT III and APL, which might stem mainly from the difference between ML and FL groups. In patients with acute stage-cerebral infarction, PA was generally and significantly lower in males than in females, especially in those having lacune.

収録刊行物

  • 脳卒中

    脳卒中 15 (1), 40-44, 1993

    一般社団法人 日本脳卒中学会

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