書誌事項
- タイトル別名
-
- The incidence of activated protein C resistance among patients suffering from stroke in Japan.
この論文をさがす
説明
Activated protein C resistance (APC-R) has recently been reported to be the most common hereditary blood coagulation disorder associated with familial thrombosis. APC-R is characterized by a poor anticoagulant response to APC in the plasma of patients the and is due to a defect of factor V. However, all the data relating to APC-R have been derived from Westerners, and little information is yet available on APC-R in Japan. We therefore studied 82 patients suffering from stroke and 33 patients with neurological disease who remained free of vascular disease, by measuring the activated partial thromboplastin time (aPTT) with and without addition of APC. We also determined whether a mutation (Arg506→ Gln) of the factor V gene was present or absent. All patients revealed an APC ratio within the normal range, and the mutation was absent in all of them. We conclude that the incidence of APC-R is very low in Japan.
収録刊行物
-
- 脳卒中
-
脳卒中 18 (1), 44-47, 1996
一般社団法人 日本脳卒中学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001204639676544
-
- NII論文ID
- 130003631206
- 10009278298
-
- NII書誌ID
- AN0020186X
-
- ISSN
- 18831923
- 09120726
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可
