Clinicopathological features of 11 resected cases of mucinous cystic neoplasms of the pancreas -Including two cases associated with pregnancy-

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  • URABE Kazuhide
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • MURAKAMI Yoshiaki
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • UEMURA Kenichiro
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • SUDO Takeshi
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • HASHIMOTO Yasushi
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • KONDO Naru
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • NAKAGAWA Naoya
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • SASAKI Hayato
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • OHGE Hiroki
    Department of Infectious Diseases, Hiroshima University Hospital
  • ARIHIRO Koji
    Department of Anatomical Pathology, Hiroshima University Hospital
  • SUEDA Taijiro
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University

Bibliographic Information

Other Title
  • 膵粘液性嚢胞腫瘍11切除例の臨床病理学的検討―妊娠期発症2例を含めて―

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Description

Mucinous cystic neoplasm of the pancreas (MCN) is a rare cystic tumor of the pancreas with malignant potential, and the disease entity of MCN is defined by ovarian-type stroma. However, some clinicopathological features and the prognoses of MCN are still unclear. We analyzed the clinicopathological features of 11 resected MCN cases with ovarian-type stroma. All patients were women, and the mean age was 52.5 years. Two patients were associated with pregnancy, including one that presented an enlarged tumor and the other presented pancreatic ascites due to rupture of the tumor. Locations of the tumors were body and tail of the pancreas in 10 patients and head in one patient. The mean size of the tumors was 72.1mm. Pathological diagnoses were invasive carcinoma in one patient and adenoma in 10 patients including the 2 patients associated with pregnancy. All patients showed no evidence of recurrence and were alive. It may be possible to select patients that can be monitored by analyzing the predictive factors of malignant MCN. We should consider the diagnosis of MCN for the abdominal cystic tumors which show rapid growth during pregnancy, and pay attention to rupture of tumors.<br>

Journal

  • Suizo

    Suizo 29 (4), 721-728, 2014

    Japan Pancreas Society

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