Present and future of cancer vaccine: WT1 peptide-based cancer immunotherapy

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  • Sugiyama Haruo
    Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine

Bibliographic Information

Other Title
  • ワクチンとＤＤＳ　　がんワクチンの現状と未来　　ＷＴ１ワクチン療法
  • がんワクチンの現状と未来--WT1ワクチン療法
  • ガン ワクチン ノ ゲンジョウ ト ミライ WT1 ワクチン リョウホウ
  • WT1 peptide-based cancer immunotherapy
  • WT1ワクチン療法

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Abstract

Wilms' tumor gene WT1 is overexpressed in leukemias and almost all types of solid tumors, and exerts an oncogenic function in leukemogenesis and tumorigenesis. WT1 protein is a pan-tumor associated antigen and we performed for the first time the WT1-peptide-based cancer immunotherapy and demonstrated its safety and clinical effect.

Journal

  • Drug Delivery System

    Drug Delivery System 23 (2), 145-150, 2008

    THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM

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