Recent progress in skin bioengineering technique and its application to percutaneous absorption

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Other Title
  • 皮膚バリア機能と皮膚を介するＤＤＳの進歩　　皮膚計測技術の進歩と物質の経皮吸収
  • 皮膚計測技術の進歩と物質の経皮吸収
  • ヒフ ケイソク ギジュツ ノ シンポ ト ブッシツ ノ ケイヒ キュウシュウ

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Abstract

Many noninvasive techniques to measure skin physiological properties have been developed in skin bioengineering field. They are measurement of water content of stratum corneum, skin surface contour, TEWL(transepidermal water loss), skin color, blood flow, sebum secretion rate and so on. In addition to above methods, recently, a few bio-microscopes which can examine the inside of the skin in vivo have been developed and applied to skin absorption of drugs. I describe in this paper the study on drug delivery using in vivo confocal Raman microscopy and multiphoton microscopy.

Journal

  • Drug Delivery System

    Drug Delivery System 22 (4), 433-441, 2007

    THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM

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