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Nanoparticle-Mediated Drug Delivery System for Coronary Artery Disease
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- Matoba Tetsuya
- Department of Cardiovascular Medicine, Kyushu University Hospital
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- Koga Jun-ichiro
- Department of Cardiovascular Research, Development, and Translational Medicine, Kyushu University Center for Cardiovascular Disruptive Innovation
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- Nakano Kaku
- Department of Cardiovascular Research, Development, and Translational Medicine, Kyushu University Center for Cardiovascular Disruptive Innovation
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- Egashira Kensuke
- Department of Cardiovascular Research, Development, and Translational Medicine, Kyushu University Center for Cardiovascular Disruptive Innovation
Bibliographic Information
- Other Title
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- 冠動脈疾患に対するナノ粒子・ドラッグデリバリーシステムの開発
- カンドウミャク シッカン ニ タイスル ナノ リュウシ ・ ドラッグデリバリー システム ノ カイハツ
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Description
Coronary artery disease including acute myocardial infarction is a significant concern in cardiovascular medicine, because of their high acute mortality and morbidity causing lethal heart failure. Atherosclerotic plaque destabilization and rupture are central pathogenesis of acute myocardial infarction, whereas myocardial ischemia-reperfusion injury is another adverse phenomenon in the heart undergoing early reperfusion therapy for acute myocardial infarction. There are un-met needs for these pathological conditions to be overcome by the use of nanoparticle-mediated drug delivery system (DDS). We provide overview of the mechanistic background for the use of DDS and the efficacy of nano-medicine in preclinical disease models.
Journal
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- Drug Delivery System
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Drug Delivery System 30 (4), 299-308, 2015
THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM
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Keywords
Details 詳細情報について
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- CRID
- 1390001204642297088
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- NII Article ID
- 130005116532
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- NII Book ID
- AN10084591
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- ISSN
- 18812732
- 09135006
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- NDL BIB ID
- 026765027
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- Text Lang
- ja
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- Article Type
- journal article
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
- KAKEN
- OpenAIRE
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- Abstract License Flag
- Disallowed