船舶レーダーのぞき作業者にみられたゴムによる慢性黒色皮膚炎

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タイトル別名
  • A CASE OF CHRONIC MELANODERMATITIS DUE TO THE RUBBER PEEPHOLE OF A SHIP-RADAR-SCOPE
  • センパク レーダーノゾキ サギョウシャ ニ ミラレタ ゴム ニヨル マンセイ

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説明

A patient with peculiar pigmentation on the face and hands was examined and it was clarified that the nature of pigmentation was chronic melanodermatitis due to the rubber covering with which he was usually in contact to look into the radar in his working ferry boat.<BR>The patient is a 40-year-old Japanese with no specific family history, working as captain of a ferry boat in the Setonaikai-line. He noticed reticular brownish black pigmentation with itchy dark reddish tone on periorbital regions, extending particularly to forehead, zygomatic regions, cheeks and nose, and the lateral margin and the back of hands about 6 months ago. These symptoms gradually increased. Histopathological examination of the left cheek with reticular pigmentation showed perivascular lymphoid infiltration and numerous melanophages in the upper dermis, and postinflammatory pigmentation was suggested. He used to look into the radar during the operation of his working ferry boat and the contact region of the rubber covering on the peephole of the radar-scope almost coincided with the peculiar pigmentation of the face. Patch tests with this rubber product and paraphenylenediamine, one of rubber antioxidants, showed positive results, but with mercaptobenzothiazole and tetramethylthiuram disulfide, accelerators producing most cases of rubber dermatitis, they were negative. As substances with similar structural formulas of paraphenylenediamine in rubber antioxidants may show cross-sensitized reactions, it was suggested that paraphenylenediamine or substituted paraphenylenediamine was contact allergens of this melanodermatitis. When the contact allergens, not so strong, continue to contact for a long time, liquefaction degeneration of basal cells occurs, then melanin granules, dropping to the dermis, are present as melanophages in the upper dermis. As such, the pigmentation seems to gradually appear. The literature reported hitherto in Japan on the chronic melanodermatitis due to rubber products is reviewed herewith.

収録刊行物

  • 産業医学

    産業医学 19 (3), 112-118, 1977

    社団法人 日本産業衛生学会

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