Effects of an Exopolysaccharide (Kefiran) from <i>Lactobacillus kefiranofaciens</i> on Blood Glucose in KKAy Mice and Constipation in SD Rats Induced by a Low-Fiber Diet

  • MAEDA Hiroaki
    Research and Development Division, Daiwa Pharmaceutical Co., Ltd.
  • ZHU Xia
    Research and Development Division, Daiwa Pharmaceutical Co., Ltd.
  • MITSUOKA Tomotari
    Professor Emeritus, The University of Tokyo

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説明

The physiologic effects of kefiran, a water-soluble exopolysaccharide, were investigated in the animal studies by oral administration of kefiran. The results in this study showed that kefiran had a hypoglycemic effect in KKAy mice and could improve defecation in the levels of fecal moisture and wet weight of feces in constipated SD rats induced by a low-fiber diet.

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