Lessening of Effective Dose in Stable Xenon-enhanced CT, Especially in Childhood Moyamoya Disease: About Serial Scan Times

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  • 小児もやもや病でのstable xenon enhanced CTを用いた脳血流量測定における実効線量軽減

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Measurement of cerebral blood flow (CBF) is necessary for the management of childhood moyamoya disease. Computed tomography (stable Xe CT) enhanced by three minutes of inhalation of stable xenon is an established method for measurement of CBF. In this retrospective study, we evaluated a decrease in serial scan times in stable Xe CT in childhood moyamoya disease in order to lessen the effective dose. <br> CBF values obtained by usually performed stable Xe CT were evaluated in 12 patients with childhood moyamoya disease. Clinically, nine serial scans were performed as usual. In this retrospective study, CBF was calculated based on nine serial scans (S9), based on seven serial scans out of the obtained nine serial scans (S7), and based on five scans out of the obtained nine serial scans (S5).<br> Both S7 and S5 had a significantly simple linear correlation with S9 as follows: <br> S9=1.642+1.031×S7, S9=2.726+0.983×S5. CBF maps obtained by S9, S7, and S5 were almost identical.<br> In childhood moyamoya disease, measurement of CBF using stable Xe CT with performance of five serial scans in each slice can be used to lessen the effective dose.<br>

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