Polydextrose as Dietary Fiber: Hydrolysis by Digestive Enzyme and Its Effect on Gastrointestinal Transit Time in Rats.
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- OKU Tsuneyuki
- Department of Nutrition, Faculty of Medicine, The University of Tokyo
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- FUJII Yasuhiro
- Saga Research Institute, Otsuka Pharmaceutical Co., Ltd.
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- OKAMATSU Hiroshi
- Saga Research Institute, Otsuka Pharmaceutical Co., Ltd.
書誌事項
- タイトル別名
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- Hydrolysis by Digestive Enzyme and Its Effect on Gastrointestinal Transit Time in Rats
説明
In order to investigate the physiological action of Polydextrose as a dietary fiber, we fed rats 3% Polydextrose diet containing either pectin or cellulose for 15 days. The effects of Polydextrose on fecal weight and gastrointestinal transit time were observed, and digestibility and the inhibitory effect of the fiber on intestinal digestive enzymes were examined. Polydextrose was partially hydrolyzed by rat intestinal mucosal homogenate, and liberated glucose increased depending on incubation time. However, Polydextrose had no inhibitory effect on the activity of disaccharidases. The combination of Polydextrose and either pectin or cellulose significantly increased fecal weight and evidently shortened transit time. The effect of Polydextrose supplementation on tissue weight was found in the cecum only, and not in other tissues. The concentration of serum constituents such as total and free cholesterol, triacylglycerol, phospholipid, and glucose was not affected by Polydextrose ingestion. These results suggest that Polydextrose partially demonstrates the dietary fiber actions such as increase in fecal volume and weight, shortening of transit time, and softening of feces.
収録刊行物
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- Journal of Clinical Biochemistry and Nutrition
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Journal of Clinical Biochemistry and Nutrition 11 (1), 31-40, 1991
一般社団法人 日本酸化ストレス学会
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詳細情報 詳細情報について
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- CRID
- 1390001204674005504
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- NII論文ID
- 130003670198
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- ISSN
- 18805086
- 09120009
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可