The effect of menopause on bone in female hemodialyzed patients.
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- Kuwahara Michio
- Second Department of Internal Medicine, Tokyo Medical and Dental University
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- Akiba Takashi
- Second Department of Internal Medicine, Tokyo Medical and Dental University
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- Kurihara Satoshi
- Kasukabe Shyuwa Hospital
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- Takeuchi Masashi
- Kasukabe Shyuwa Hospital
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- Sakurai Yuusei
- Kasukabe Shyuwa Hospital
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- Suga Masaru
- Kasukabe Shyuwa Hospital
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- Yoneshima Hideo
- Kasukabe Shyuwa Hospital
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- Marumo Fumiaki
- Second Department of Internal Medicine, Tokyo Medical and Dental University
Bibliographic Information
- Other Title
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- 女性血液透析患者の骨に対する閉経の影響
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Abstract
We investigated the effect of menopause on bone in female hemodialyzed patients. The patients were divided into two groups, pre-menopausal (PRE, n=16) and post-menopausal (POST, n=32). Mean age at menopause in the POST group was 45.1 years, i.e., 4-5 years younger than in healthy Japanese females. Bone mineral density (BMD) of the lumbar spine (L2-L4) was measured by dual-energy X-ray absorptiometry. BMD was negatively correlated with age in the POST group (r=-0.68), but no such correlation was observed in the PRE group. The decrease in lumbar spine BMD estimated from the slope of the linear regression line was 0.0106g/cm2/year in the POST group. We measured lumbar spine BMD 3-7 times over 2-4 years in 17 patients under 50 years of age (n=10 in the PRE group and n=7 in the POST group). The mean decrease in lumbar spine BMD was 0.0057g/cm2/year in the PRE group and 0.0339g/cm2/year in the POST group.<br>These findings suggest that post-menopausal osteoporosis is one of causes of bone loss in female hemodialyzed patients.
Journal
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- Nihon Toseki Igakkai Zasshi
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Nihon Toseki Igakkai Zasshi 28 (5), 879-884, 1995
The Japanese Society for Dialysis Therapy
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Details 詳細情報について
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- CRID
- 1390001204674631040
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- NII Article ID
- 130003721317
- 10005560995
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- NII Book ID
- AN10432053
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- ISSN
- 1883082X
- 13403451
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed