胸水型肺癌(癌性胸膜炎)の治療胸膜癒着術とCT所見を中心にした検討

書誌事項

タイトル別名
  • Adhesion Therapy for Lung Cancer with Massive Pleural Effusion (Pleuritis Carcinomatosa) Adhesion Therapy and Evaluation by CT Scan.

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説明

Ten patients with pleuritis carcinomatosa due to lung cancer accompanied by massive effusion were treated by tube drainage of effusion followed by instillation of MMC and OK-432 (adhesion therapy). Pleural effusion was controlled in all patients without recurrence but one showed reaccumulation 2 months later. Acute side effects of fever and chest pain were tolerable.<BR>The average hospital stay for patients receiving adhesion therapy alone was 34 days, versus 93 days for patients receiving tube drainage therapy and radiotherapy. The average survival time for 7 patients who died of this disease was 273 days.<BR>Serial CE-CT scans were useful to evaluate the stage of the disease and decide on therapeutic and follow-up policy. All cases had mediastinal metastasis (N2-3). On follow up CT scan, marked pleural thickening and varying degree of loss of lung volume were noticed. Individual cases with life expectancy several months are best managed by tube drainage and instillation of adhesion-inducing agents.

収録刊行物

  • 肺癌

    肺癌 36 (3), 253-259, 1996

    特定非営利活動法人 日本肺癌学会

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