A case of Lansoprazole-associated collagenous colitis in a hemodialysis patient

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  • 透析患者に発症したランソプラゾール関連性ｃｏｌｌａｇｅｎｏｕｓ　ｃｏｌｉｔｉｓの１例
  • 症例報告 透析患者に発症したランソプラゾール関連性collagenous colitisの1例
  • ショウレイ ホウコク トウセキ カンジャ ニ ハッショウ シタ ランソプラゾール カンレンセイ collagenous colitis ノ 1レイ

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Abstract

An 81-year-old male on maintenance hemodialysis since December 2008 had been taking various medications including Lansoprazole. The patient developed symptoms of chronic watery diarrhea in March 2009. On colonoscopy, a longitudinal ulcer was noted on the left side of the colon. Biopsy speciments demonstrated thickened subepithelial collagen bands. After discontinuing Lansoprazole, the patient's symptom improved. The patient's clinical and histological findings were compatible with a diagnosis of Lansoprazole-associated collagenous colitis. Many hemodialysis patients have been administered proton pump inhibitors such as Lansoprazole. If a hemodialysis patients with chronic diarrhea has been taking Lansoprazole, the possibility of collagenous colitis should be considered.

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