Heparin-induced thrombocytopenia (HIT) in hemodialysis patients experienced in our hospital

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  • 当院で経験した血液透析患者に合併したヘパリン起因性血小板減少症 (heparin-induced thrombocytopenia : HIT)
  • 症例報告 当院で経験した血液透析患者に合併したヘパリン起因性血小板減少症(heparin-induced thrombocytopenia : HIT)
  • ショウレイ ホウコク トウ イン デ ケイケン シタ ケツエキ トウセキ カンジャ ニ ガッペイ シタ ヘパリン キインセイ ケッショウバン ゲンショウショウ(heparin-induced thrombocytopenia : HIT)

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Abstract

 We experienced 5 cases of HIT among hemodialysis patients (HIT during dialysis) from 1 July, 2008, to 31 Aug, 2012. We show the clinical characteristics of these cases compared with those of 74 patients starting dialysis (emergency dialysis in 32 patients) during the same period in our hospital. All of these 5 cases experienced HIT during the period of introduction of emergency dialysis using intravascular catheters. Given that the incidence of HIT during the hemodialysis introduction period was 6.8% (5/74 cases), the incidence in patients starting emergency dialysis using intravascular catheters was considered to be high at 15.6% (5/32 cases). Six out of 74 cases experienced intravascular catheter blockage at least twice, and 4 cases among them developed HIT. The HIT antibody did not become negative in 1 patient, who died of another disease. All 4 cases negative for HIT antibody received heparin administration again, and their clinical courses have been uneventful without recurrence to date.

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