成人肺の気管支樹における粘液腺の分布と組織学的観察に関する研究

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  • Studies on distribution and histological observation of mucus gland in the bronchial tree of adult human lungs

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Systemic observation of mucus gland in the bronchial tree has been done in present report by methods of photomicroscopy and electronmicroscopy. Specimens were obtained from autopsied and surgical resected lungs. 258 trees and 1, 331 specimens from bronchial trees were observed from the first (lobar), the second (segmental), the third (subsegmental), the fourth, the fifth, the sixth, the seventh, the eighth, and to the nineth bronchus. The same morphological pattern of mucus gland was observed in the bronchial wall from the first to fourth bronchus. One type of mucus gland was found between bronchial mucosa and cartilage, and the other was between cartilage and cartilage. The former type of mucus gland disappeared in the fifth and sixth bronchus. The combination of mucus gland and cartilage was observed 78.5% of the fifth bronchus, but only 11.3% of sixth bronchus. There were no existence of mucus gland and cartilage in the wall of the seventh, eighth, and the nineth bronchus. Histogenetically, benign and malignant tumors of mucus gland origin could be developed from the first to sixth bronchus and not be from the seventh, eighth, and the nineth bronchus. Carcinoid and oat-cell carcinoma could be originated from the both side of mucus gland and bronchial mucosa, which was revealed the co-existence of Kultschitzky cell by the electronmicroscopic observation.

収録刊行物

  • 肺癌

    肺癌 14 (1), 21-29, 1974

    特定非営利活動法人 日本肺癌学会

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