書誌事項
- タイトル別名
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- Study on Hemostatic Management in Hemophilia A - Usefullness of APTT and TEG as the Method for Monitoring Factor VIII Concentrates-
この論文をさがす
抄録
The transfution effects of factor VIII concentrates (Conco-eight) were performed in two cases of hemophilia A whose levels of the antihemophilic plasma factor VIII were less than 2.5 per cent. The factor VIII concentrates must usually be monitored in cases of dental treatment such as tooth extraction for these patients. However, the method of monitoring is very expensive and troublesome work, so we investigated the use of APTT and TEG as the monitoring methods. The folloing conclusions were obtained.:<BR>(1) Among the effects of transfution factor VIII, the values of APTT and TEG were lowest when the factor VIII values were highest.<BR>(2) There were significant positive correlations in both cases between factor VIII and the level of APTT(activity) (p<0.001), while in relation to TEG (r+k) were observed negative correlations (p<0.001). However, there were a few variations in each case respectively.<BR>(3) As a result of the calculation of the level of factor VIII concentrates from the lower normal limits of APTT(70%) and of TEG(r+k=18 minute), the former corresponded to about 30 per cent of factor VIII concentrates and the later was about 20 per cent.
収録刊行物
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- The Japanese Journal of Pediatric Dentistry
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The Japanese Journal of Pediatric Dentistry 23 (3), 760-768, 1985
The Japanese Society of Pediatric Dentistry