書誌事項
- タイトル別名
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- Experimental Studies on the Biocompatibility between Deciduous Crown, Distal-shoe and Rat Subcutaneous Tissue
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説明
The biocompatibility of pure nickel, two types of deciduous crowns, and the distal-shoe, which have been applied in pediatric dentistry, were evaluated histopathologically and biochemically, and the subcutaneous tissue of experimental rats were used in this study.<BR>The macroscopical observation revealed that the tissue around the nickel had shown severe inflammatory changes accompanied by swelling and redness. On the seventh day of the experiment, histopathological examination revealed that these masses showed the following findings; a necrotized tissue in contact with the nickel, a severe inflammatory tissue layer with inflammatory cell infiltration, a narrow bleeding layer, and a network-structure of fibrous tissue with numerous capillaries. The tissue had been gradually affected by the nickel. After ninety days, eosinophilic amorphous masses were seen around the nickel, which was surrounded by granulation tissue and connective tissue layers with numerous inflammatory cell infiltration and capillaries. A large amount of Ni2++ was detected in the subcutaneous tissue around the nickel metal in all of the experimental animals. The tissue around the two deciduous crowns and the distal-shoe showed that the almost all of the experiments did not reveal any gross changes nor did the histopathological findings.<BR>The tissues around the metal were composed of fine fibrous tissue layers without inflammatory cell infiltration and granular foci, which revealed good biocompatibility. A small amount of Ni2++ was, however, detected in the tissue around these metals.<BR>These findings have indicated that the alloys were corroded, and the nickel had been released from the alloys as Ni2++ or Ni compounds and Ni2++ remained in the tissue without any changes.<BR>These experimental studies have shown that nickel as a metal would cause of serious inflammatory reactions in the tissue. Although the tissue is not affected by the alloys, a small amount of Ni2++ could be detected with the atomic absorption method.
収録刊行物
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- The Japanese Journal of Pediatric Dentistry
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The Japanese Journal of Pediatric Dentistry 23 (2), 378-387, 1985
The Japanese Society of Pediatric Dentistry
