Ovarian stromal Leydig cell tumor with prominent crystalloids of Reinke. Report of a case.

  • ARAI Masahide
    Department of Obstetrics and Gynecology, Kitasato University School of Medicine
  • JOBO Toshiko
    Department of Obstetrics and Gynecology, Kitasato University School of Medicine
  • SATO Rinya
    Department of Obstetrics and Gynecology, Kitasato University School of Medicine
  • WATANABE Jun
    Department of Pathology, Kitasato University School of Medicine
  • IWAYA Hiroaki
    Department of Obstetrics and Gynecology, Kitasato University School of Medicine
  • KURAMOTO Hiroyuki
    Department of Obstetrics and Gynecology, Kitasato University School of Medicine

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Other Title
  • Reinke crystalが目立った卵巣間質性ライディク細胞腫の1例
  • Report of a case

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A case of stromal Leydig cell tumor with prominent crystalloids of Reinke is presented. In pathological specimens, the tumor arose in a background of ovarian stromal cell proliferation with foci of Leydig cells. The stromal component of the tumor resembled fibroma and Leydig cells had abundant eosinophilic cytoplasm and prominent Reinke crystalloids. A small lesion of mucinous cystadenoma coexisted with this tumor. Imprint cytology of the tumor revealed 3 types of the tumor cells. I. Spindle-shaped cells with scanty cytoplasm forming loose clusters, 2. Cells with abundant light green-stained cytoplasm and oval nuclei which consisted of stratified clusters, 3. Cells showing a palisading pattern. Rod-shaped and orange-G stained crystalloids (crystalloids of Reinke) were observed frequently within cellular clusters of the 2 types.

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