Cellular manifestation of uterine leiomyosarcoma combined with epithelioid clusters. Report of a case.

DOI
  • HATTORI Manabu
    Division of Cytology, Department of Pathology, Kitasato University Hospital
  • OHNO Eiji
    Division of Cytology, Department of Pathology, Kitasato University Hospital
  • YOKOYAMA Masaru
    Division of Cytology, Department of Pathology, Kitasato University Hospital
  • TAKAYAMA Akiko
    Division of Cytology, Department of Pathology, Kitasato University Hospital
  • TOYONAGA Masumi
    Division of Cytology, Department of Pathology, Kitasato University Hospital
  • KUWAO Sadahito
    Department of Pathology, School of Medicine, Kitasato University
  • KURAMOTO Hiroyuki
    Department of Obstetrics and Gynecology, School of Medicine, Kitasato University

Bibliographic Information

Other Title
  • 上皮様結合を示す腫よう細胞集塊が出現した子宮体部平滑筋肉腫の１例

Abstract

A case of uterine leiomyosarcoma which was difficult todiagnose cytologically because of the presence of epithelioidclusters is reported.Three different cellular componentsincluding scattered spindle-shaped and giant cells, and epithelioidclusters, first suggested Miillerian mixed tumor.Immunocytochemistrystudies, however, were positive for desmin, vimentin and smooth muscle actin, but negative for CEA, EMA, SC and myoglobin, indicating the same origin as smooth muscle.Retrospective examination of Papanicolaou -stained specimens revealed common findings of finely granulated chromatin and thin nuclear borders in these cells. It is concluded that detailed analysis of nuclear borders and chromatin patterns is mandatory to clarify the origin of the cells, especially in the case of stump specimens of uterine leiomyosarcoma.

Journal

Keywords

Details 詳細情報について

  • CRID
    1390001204693300992
  • NII Article ID
    130003926174
  • DOI
    10.5795/jjscc.33.1160
  • ISSN
    18827233
    03871193
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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