A Case of Swine Amyloidosis Associated with Granulomatous Mastitis

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  • 肉芽腫性乳腺炎に続発した豚のアミロイド症の1例
  • 肉芽腫性乳腺炎に続発した豚のアミロイド症の1例(短報)
  • ニクゲシュセイ ニュウセンエン ニ ゾクハツシタ ブタ ノ アミロイドショウ

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Abstract

Systemic amyloidosis was observed in a 2-year-old, Landrace-breed sow. Amyloid deposits were observed in the liver, spleen, kidney, small intestine, and many lymph nodes. These were stained faintly red with hematoxylin-eosin, and yellowish-red with congo red, which showed emerald-green birefringence under polarized light. Amyloid protein was sensitive to the potassium permanganate treatment losing affinity for congo red, and reacted positive for the anti-AA antibody. The present case was diagnosed to be secondary systemic amyloidosis which was immunohistochemically confirmed to be a deposit of AA protein, associated with granulomatous mastitis caused by Actinomyces sp.

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