Chemotactic Response of Bovine Neutrophils Evaluated by Chemotaxis under Agarose

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  • ウシ好中球の走化能の測定
  • ウシ コウチュウキュウ ノ ソウカノウ ノ ソクテイ

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Abstract

Zymosan-activated serum showed a significant chemotactic activity, whereas formyl peptide f-MLP failed to attract bovine neutrophils. An optimal number of neutrophils and incubation period in the agarose method were 1×106 neutrophils and 2 hours, respectively.<BR>A significantly reduced chemotactic response of neutrophils in cows was found immediately after the parturient period, as compared with that in any other period. This reduction seemed to be related to the elevated cortisol concentration in blood during the parturient period.

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