The Time Course of C-Reactive Protein in a Dog Suffering Acute Pancreatitis

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  • 急性膵炎の犬においてC-反応性蛋白を経時的に観察した1例
  • 日本小動物獣医学会会誌 急性膵炎の犬においてC-反応性蛋白を経時的に観察した1例
  • ニホン ショウドウブツ ジュウイガッカイカイシ キュウセイスイエン ノ イヌ ニ オイテ C ハンノウセイ タンパク オ ケイジテキ ニ カンサツ シタ 1レイ

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Abstract

A female Shetland sheepdog was referred to us suffering from depression, anorexia and bloody diarrhea. Aphysical examination demonstrated abdominal pain. Hematological examination revealed an increase in WBC, and a serum chemistry analysis revealed an increment in serum alkaline phosphatase, amylase and lipase.Serum CRP levels markedly increased at 51mg/dl. The dog was therefore diagnosed as suffering from acutepancreatitis. For primary care, NPO (nothing by mouth) was conducted for three days, and antibiotic andgabexate mesilate were administrated intravenously. On the second day, the WBC and serum lipase increased, but serum CRP levels decreased compared with the first day. After 12 days, the dog was discharged from theveterinary hospital with vitality and appetite restored. In the current case, the measurement of serum CRP levelswas effective in evaluating the condition of acute pancreatitis. Moreover, serial serum CRP measurementswere effective in predicting the efficacy of treatment.

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