Control of hydroxyapatite crystal growth by gallic acid

  • TANG Bei
    State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University Department of Endodontics and Operative Dentistry, West China Hospital of Stomatology, Sichuan University
  • YUAN He
    State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University Department of Endodontics and Operative Dentistry, West China Hospital of Stomatology, Sichuan University
  • CHENG Lei
    State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University Department of Endodontics and Operative Dentistry, West China Hospital of Stomatology, Sichuan University
  • ZHOU Xuedong
    State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University Department of Endodontics and Operative Dentistry, West China Hospital of Stomatology, Sichuan University
  • HUANG Xuelian
    State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University Department of Endodontics and Operative Dentistry, West China Hospital of Stomatology, Sichuan University
  • LI Jiyao
    State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University Department of Endodontics and Operative Dentistry, West China Hospital of Stomatology, Sichuan University

書誌事項

公開日
2015
資源種別
journal article
DOI
  • 10.4012/dmj.2014-175
公開者
一般社団法人 日本歯科理工学会

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説明

The purpose of this study is to detect the effect of gallic acid (GA) on hydroxyapatie crystal growth and find the mechanism of the regulation. We evaluated the morphology of HAP crystals grown under various amounts of GA (0, 0.05, 1, and 4 gL−1). Subsequently, the chemical composition, crystal size and the morphology were investigated via the energy-dispersive X-ray spectrometer, attenuated total fourier transform infrared spectroscopy, thermogravimetric analysis, X-ray diffraction analysis, transmission electron microscope and scanning electron microscopy. In all groups, the Ca/P ratio was closed to 1.67. In the absence of GA, crystals did not arrange, while in the presence of GA, crystals tended to form spherules. The size of the crystals decreased with the concentration of GA increased. These results indicated the role of GA on the growth and morphology of hydroxyapatite crystals, which might be the key mechanism for gallic acid regulating the mineralization.

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