Rapid Inhalation Induction of Anesthesia with 5% Isoflurane or Sevoflurane in Dogs.

  • MUTOH Tatsushi
    Department of Veterinary Surgery, Faculty of Agriculture, The University of Tokyo
  • NISHIMURA Ryohei
    Department of Veterinary Surgery, Faculty of Agriculture, The University of Tokyo
  • KIM Hwi-yool
    Department of Veterinary Medicine, College of Animal Husbandry, Kon-Kuk University
  • MATSUNAGA Satoru
    Department of Veterinary Surgery, Faculty of Agriculture, The University of Tokyo
  • KADOSAWA Tsuyoshi
    Department of Veterinary Surgery, Faculty of Agriculture, The University of Tokyo
  • MOCHIZUKI Manabu
    Department of Veterinary Surgery, Faculty of Agriculture, The University of Tokyo
  • SASAKI Nobuo
    Department of Veterinary Surgery, Faculty of Agriculture, The University of Tokyo

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Other Title
  • 犬におけるイソフルラン, セボフルラン, 笑気による高濃度急速マスク導入法の応用

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Rapid inhalation induction of anesthesia (RI) using 5 % isoflurane or sevoflurane with or without 67% of nitrous oxide (OI, GOT, OS and GOS) was evaluated by compaing the movements, induction and intubation time, and the cardiovascular effects in 24 beagle dogs. Induc tion time of anesthesia (223.7±29.2 sec) in OI group was significantly shorter than that in OS group (310.2±33.9 sec) . In addition, induction of anesthesia was more rapid and smoother with the use of nitrous oxide (GOT: 206.2±24.4 sec, GOS: 260.8±22.2 sec) . All the dogs of any groups showed various degree of movements during induction. However, in GOT group, movements in half of the dogs were minimal. The changes in cardiac parameters after the beginning of inhalation was remarkable, especially in heart rate. However, stabilization on circulatory and respiratory function under the maintenance level (1.5 MAC) could be attained in 10 min. Therefore, GOI is the most practical method for RII in dogs wihtout undesired effects on the airway when the maximum scale of the commercial vaporizer (5%) was used.

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