Efficacy of Carboplatin and Radiation on Malignant Histiocytosis in a Bernese Mountain Dog

DOI Web Site 9 References
  • ECHIGO Ryosuke
    Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • ANDOH Mari
    Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • NAKAYAMA Hiroyuki
    Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • NISHIMURA Ryohei
    Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • MATSUNAGA Satoru
    Laboratory of Veterinary Emergency Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • SASAKI Nobuo
    Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo

Bibliographic Information

Other Title
  • バーニーズマウンテンドッグの悪性組織球症にカルボプラチン投与と放射線療法の併用が効果を示した一例
  • バーニーズマウンテンドッグ ノ アクセイ ソシキキュウショウ ニ カルボプラチン トウヨ ト ホウシャセン リョウホウ ノ ヘイヨウ ガ コウカ オ シメシタ イチレイ

Search this article

Abstract

A 6-year-old Bernese mountain dog was presented with a large subcutaneous mass diagnosed as malignant histiocytosis on the left forelimb. Although the mass and the regional lymph node were surgically resected, the mass recurred in 3 days. Then the orthovoltage radiation (total 36 Gy) and chemotherapy with carboplatin (300 mg/m2, 9 times) were conducted over 6 months after the surgery. In 6 months, the mass was completely disappeared without any recurrence and metastasis. However, after the complete remission for over 450 days, the tumor recurrence was observed on 684 days after the first admission, and the left forelimb was amputated due to pathologic fracture. At 850 days after the first admission, pulmonary metastasis was observed, and the owner did not want further treatments. Although this malignant neoplasia is difficult to cure, adjunctive carboplatin administration and radiation may be one of the effective treatments for malignant histiocytosis in Bernese mountain dogs.<br>

Journal

References(9)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top