下咽頭癌における外側咽頭後（ルビエール）リンパ節転移症例の検討

DOI 被引用文献2件 参考文献13件 オープンアクセス

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タイトル別名
  • INVESTIGATION OF LATERAL RETROPHARYNGEAL LYMPH NODE IN CARCINOMA OF THE HYPOPHARYNX

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説明

It is accepted that carcinoma of the hypopharynx has a tendency to metastasize to the neck lymph nodes. In addition, a common fatal prognostic factor is metastasis to the lateral retropharyngeal nodes (Rouviere's lymph nodes). In this study, we reviewed retrospectively metastases to lateral retropharyngeal nodes in 214 hypopharyngeal cancer patients who were treated in Kurume University Hospital and analyzed the prognostic factors.<br>Metastases to Rouviere's lymph nodes were found in 21 (10%) of 214 patients (stage I: 0%, II: 3%, III: 10%, IV: 12%).<br>The cause-specific five-year survival rate determined using the Kaplan-Meier method was 69% for patients with negative Rouviere's lymph nodes and 41% for patients with positive Rouviere's lymph nodes. There was a statistically significant difference between the two survival rates (p<5%).<br>Fourteen (19%) of 76 patients who underwent retropharyngeal lymph nodes dissection had pathologically positive nodes. Distant metastasis was detected in 8 (13%) of the 62 patients whose retropharyngeal lymph nodes were pathologically negative. On the contrary, 6 (43%) of the 14 patients whose retropharyngeal nodes were pathologically positive had distant metastases. There was a statistically significant difference in the rate of distant metastases (p<1%) between them.<br>Eleven patients whose retropharyngeal lymph nodes at neck dissection were pathologically positive and received additional radiotherapy did not show recurrence in the Rouviere's lymph nodes.<br>These results highly support the efficacy of retropharyngeal lymph nodes dissection and postoperative irradiation for the Rouviere's lymph nodes in hypopharyngeal carcinomas.

収録刊行物

  • 頭頸部腫瘍

    頭頸部腫瘍 30 (1), 47-52, 2004

    日本頭頸部癌学会

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