Report of guidelines for patients on antithrombotic therapy requiring dental extraction

  • MATSUNO TOMONORI
    Department of Oral and Maxillofacial Surgery, The Nippon Dental University, School of Life Dentistry at Tokyo
  • AMAGASA TERUO
    Maxillofacial Surgery, Graduate School, Tokyo Medical and Dental University
  • KANEKO AKIHIRO
    Department of Oral Surgery, Division of Surgery, Tokai University school of Medicine
  • KITAHARA KAZUKI
    Department of Oral and Maxillofacial Surgery, The Nippon Dental University, School of Life Dentistry at Tokyo
  • ASADA KOICHI
    Second Department of Oral and Maxillofacial Surgery at Tsurumi University School of Dental Medicine
  • SATOH TAZUKO
    Department of Oral and Maxillofacial Surgery, The Nippon Dental University, School of Life Dentistry at Tokyo

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Other Title
  • 「抗血栓療法患者における抜歯のガイドライン」に関する報告

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Abstract

The objectives of report were: 1) to identify the guidelines for the management of patients on antithrombotic therapy requiring dental extraction; 2) to summarize the evidence and recommendations; and 3) to provide guidance for the dentists on identifying which patients can be managed in primary care.<br>We searched systematically for literatures in several electronic databases, focusing on dental surgery in patients receiving continuous antithrombotic therapy.<br>The following evidence-based recommendations were organized; (1) for patients within the stably therapeutic range of International Normalized Ratio (INR: 2.0-3.5), anticoagulant therapy continued for dental extraction with appropriate local haemostatic measures. (2) A check INR is recommended 72 hours prior to dental extraction. (3) It is not necessary to interrupt low-dose aspirin therapy (100mg/day or less) for dental extraction.

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