Improvement of a Case of Intestinal Behçet’s Disease After the Postoperative Administration of a Low-dose Adrenocortical Steroid
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- Sato Kentaro
- Department of Gastrointestinal Surgery, Hirosaki University Hospital Department of Surgery, Mutsu General Hospital
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- Umemura Kotaro
- Department of Surgery, Mutsu General Hospital
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- Hasebe Tatsuya
- Department of Gastrointestinal Surgery, Hirosaki University Hospital Department of Surgery, Mutsu General Hospital
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- Yamada Kyogo
- Department of Surgery, Mutsu General Hospital
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- Matsuura Osamu
- Department of Surgery, Mutsu General Hospital
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- Hashizume Tadashi
- Department of Surgery, Mutsu General Hospital
Bibliographic Information
- Other Title
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- 盲腸穿孔で発症した腸管ベーチェット病に対し術後低用量ステロイド投与が著効した1例
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Description
<p>We report a case of intestinal Behçet's disease that improved with the postoperative administration of a low-dose adrenocortical steroid. Ileocecal resection was performed on a 24-year-old woman diagnosed with a perforated punched-out ulcer of the cecum. After surgery, the patient developed fever and melena, and a blood test indicated a marked inflammatory response. Behçet's disease was diagnosed based on the findings of the physical examination and an analysis of the resected specimen. The patient was started on a low-dose adrenocortical steroid (100 mg/day of hydrocortisone, equivalent to 25 mg/day of prednisolone). Following the administration of hydrocortisone, the patient's symptoms and physical examination data significantly improved. Adrenocortical steroids are administered as a remission-induction therapy for intestinal Behçet's disease. However, intestinal perforation is associated with a risk of bacterial infection, so the decision to administer steroids can be a difficult one. Although there is no consensus on the appropriate dose of steroid to be used in these cases, low-dose steroids may improve the patient's condition, as was seen in our case. In patients with intestinal perforation, low-dose steroids may be useful for the treatment of Behçet's disease, while minimizing the risk of infection.</p>
Journal
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- Nihon Fukubu Kyukyu Igakkai Zasshi (Journal of Abdominal Emergency Medicine)
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Nihon Fukubu Kyukyu Igakkai Zasshi (Journal of Abdominal Emergency Medicine) 37 (5), 779-782, 2017
Japanese Society for Abdominal Emergency Medicine
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Details 詳細情報について
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- CRID
- 1390001204738394880
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- NII Article ID
- 130006243182
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- ISSN
- 18824781
- 13402242
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed