Improvement of a Case of Intestinal Behçet’s Disease After the Postoperative Administration of a Low-dose Adrenocortical Steroid

DOI
  • Sato Kentaro
    Department of Gastrointestinal Surgery, Hirosaki University Hospital Department of Surgery, Mutsu General Hospital
  • Umemura Kotaro
    Department of Surgery, Mutsu General Hospital
  • Hasebe Tatsuya
    Department of Gastrointestinal Surgery, Hirosaki University Hospital Department of Surgery, Mutsu General Hospital
  • Yamada Kyogo
    Department of Surgery, Mutsu General Hospital
  • Matsuura Osamu
    Department of Surgery, Mutsu General Hospital
  • Hashizume Tadashi
    Department of Surgery, Mutsu General Hospital

Bibliographic Information

Other Title
  • 盲腸穿孔で発症した腸管ベーチェット病に対し術後低用量ステロイド投与が著効した1例

Search this article

Abstract

<p>We report a case of intestinal Behçet's disease that improved with the postoperative administration of a low-dose adrenocortical steroid. Ileocecal resection was performed on a 24-year-old woman diagnosed with a perforated punched-out ulcer of the cecum. After surgery, the patient developed fever and melena, and a blood test indicated a marked inflammatory response. Behçet's disease was diagnosed based on the findings of the physical examination and an analysis of the resected specimen. The patient was started on a low-dose adrenocortical steroid (100 mg/day of hydrocortisone, equivalent to 25 mg/day of prednisolone). Following the administration of hydrocortisone, the patient's symptoms and physical examination data significantly improved. Adrenocortical steroids are administered as a remission-induction therapy for intestinal Behçet's disease. However, intestinal perforation is associated with a risk of bacterial infection, so the decision to administer steroids can be a difficult one. Although there is no consensus on the appropriate dose of steroid to be used in these cases, low-dose steroids may improve the patient's condition, as was seen in our case. In patients with intestinal perforation, low-dose steroids may be useful for the treatment of Behçet's disease, while minimizing the risk of infection.</p>

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top