メペリジン持続皮下注による小児の術後鎮痛の試み
書誌事項
- タイトル別名
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- Postoperative Analgesia in Children Using Continuous Subcutaneous Infusion of Meperidine.
説明
Continuous subcutaneous infusion of meperidine was compared with infusion of morphine for pain relief in 19 patients (9-19 years, weight 19.2-57.6kg) after major orthopedic surgery. 11 children received meperidine, and 8 received morphine. After surgery, a 25-gauge butterfly needle was inserted subcutaneously in the anterior chest.<br>Patients received meperidine at a rate of 38-687μg•kg-1•h-1 for 45.0-115.8hours, and morphine at 4.5-46μg•kg-1•h-1 for 38.5-83.3hours. The total amount of drug per patient was 185.0-1, 207.5mg for meperidine, and 19.8-71.1mg for morphine. Both of them brought about a satisfactory analgesia.<br>Abdominal distension, nausea or vomiting occurred in 7 of 8 patients taking morphine, but only 7 of 11 patients suffered from mild gastrointestinal side effects in the meperidine group. Neither respiratory depression nor excessive sedation was observed in any patient.<br>Meperidine was as effective as morphine for postoperative analgesia but with less gastrointestinal side effects.<br>We concluded that continuous subcutaneous meperidine infusion is a safe and effective method for postoperative pain relief.
収録刊行物
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- 日本臨床麻酔学会誌
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日本臨床麻酔学会誌 19 (9), 561-566, 1999
日本臨床麻酔学会
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詳細情報 詳細情報について
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- CRID
- 1390001204759990016
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- NII論文ID
- 130003581646
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- ISSN
- 13499149
- 02854945
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
