中等度強度の持久的運動負荷が経口摂取飲料の胃排出機能および吸収機能に及ぼす影響―FDG‐PETを用いた検討

DOI

書誌事項

タイトル別名
  • EFFECT OF MODERATE INTENSITY EXERCISE ON GASTRIC EMPTYING AND ABSORPTION USING PET TECHNIQUE

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説明

The purpose of this study was to investigate the effect of moderate intensity exercise on gastric emptying and absorption using positron emission tomography(PET)with oral 18F-fluoro-deoxy-glucose(18FFDG) intake. Seven healthy subjects aged 20~28 years volunteered to participate in this study. Each subject exercised on a bicycle ergometer for 30 minutes at 60% maximal oxygen uptake(Exercise trial). A control trial(without exercise)was also performed by the subjects. Immediately before starting exercise, 300ml of water containing 18F-FDG was orally administered. 18F-FDG accumulation in the alimentary tract was measured with 3D PET after the end of exercise. Regions of interest were drawn on visually defined stomach and small intestine. To measure blood glucose, plasma radioactivity, and plasma CCK, blood was sampled 4 times every 10 minutes throughout the exercise. Percent contents of remaining radioactivity in stomach in exercise trial was higher than that in control. Significant change in blood glucose level due to exercise was showed. Plasma CCK level in exercise trial was higher than that in control at the end of exercise. The effect of exercise on %contents of remaining radioactivity in the total alimentary tract or change in plasma radioactivity level was not significant. These findings suggest that cycling exercise for 30 minutes at moderate intensity has a depressive effect on gastric emptying of fluid intake partially influenced by CCK, but no marked effect on absorption of 18F-FDG from the intestine in normal human subjects.

収録刊行物

  • 体力研究

    体力研究 101 (0), 1-7, 2003

    公益財団法人 明治安田厚生事業団 体力医学研究所

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