High-definition optical coherence tomography underneath tissue surface

DOI 1 Citations 25 References
  • Ohmi Masato
    Course of Allied Health Sciences, Graduate School of Medicine, Osaka University
  • Haruna Masamitsu
    Course of Allied Health Sciences, Graduate School of Medicine, Osaka University

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  • 生体表皮下の高精細ＯＣＴ

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Description

Optical coherence tomography (OCT) is a very promising technique for clinical diagnosis because high-resolution tomography is easily obtained by a compact imaging optics. The existing OCT, however, should be improved toward high-definition OCT which is comparable to a histology (or a microscopic photograph of tissue). In this paper, we summarized our recent effort to approach to high-definition OCT. In in-vitro tomographic imaging of the human stomach wall, in-focus OCT could provide a very clear image of the muscularis mucosae of a few tens of microns thickness. Furthermore, we demonstrated high-definition OCT of micro tissue structures including epidermis, dermis and stratum basale using a femtosecond Ti:sapphire laser.

Journal

  • Nippon Laser Igakkaishi

    Nippon Laser Igakkaishi 26 (3), 239-244, 2005

    Japan Society for Laser Surgery and Medicine

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