Evidence-based medicine. How to treat the patients with Meniere's disease.
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- Takeda Noriaki
- Department of Otolaryngology, University of Tokushima School of Medicine
Bibliographic Information
- Other Title
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- メニエール病の治療におけるEBM
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Description
For the treatment of patients with Meniere's disease in the acute period, randomized controlled trials showed that anti-vertigo drugs, such as diphenidol and betahistine, are significantly effective. In the chronic period, Meniere's disease is specifically managed by osmotic diuretic, isosorbide. The dose comparative study showed that its opitimal dose is 90ml/day. Despite many controversies against endolymphatic sac surgery, including the Danish sham surgery study suggesting a placebo effect of mastoidectomy, the efficacy of the procedure is widely accepted. However, it is not clear that endolymphatic sac surgery alters the natural history of Meniere's disease in a long term.
Journal
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- Otology Japan
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Otology Japan 10 (3), 147-149, 2000
Japan Otological Society
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Details 詳細情報について
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- CRID
- 1390001204769427968
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- NII Article ID
- 10009320187
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- NII Book ID
- AN10358085
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- ISSN
- 18841457
- 09172025
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed