A case of suspected perilymphatic oozer with CTP-positive cerebrospinal otorrhea

DOI 23 References
  • Fukuda Junya
    Department of Otolaryngology, University of Tokushima School of Medicine
  • Goda Masakazu
    Department of Otolaryngology, University of Tokushima School of Medicine
  • Fujimoto Chisa
    Department of Otolaryngology, University of Tokushima School of Medicine
  • Ikezono Tetsuo
    Department of Otolaryngology, Saitama Medical University
  • Nakagawa Takashi
    Department of Otolaryngology, Fukuoka University Faculty of Medicine
  • Hibino Hiroshi
    Department of Molecular Physiology, Niigata University Medical School
  • Kitamura Yoshiaki
    Department of Otolaryngology, University of Tokushima School of Medicine
  • Abe Koji
    Department of Otolaryngology, University of Tokushima School of Medicine
  • Tamura Koichi
    Department of Otolaryngology, University of Tokushima School of Medicine
  • Takeda Noriaki
    Department of Otolaryngology, University of Tokushima School of Medicine

Bibliographic Information

Other Title
  • Perilymphatic oozerが疑われたCTP陽性の耳性髄液漏症例

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Description

We reported a case of suspected perilymphphatic oozer. The patient visited our hospital 3 years after head trauma and complained of refractory watery otorrhea from the left ear and moderate mixed hearing loss, but no vertigo/dizziness. Her otorrhea was positive for CTP (cochlin-tomoprotein), which is a perilymph-specific protein. Because CTP can be used as a diagnostic marker of perilymph leakage, the diagnosis of perilymphatic fistula was made in the patient. In addition, her otorrhea contained high concentration of glucose and radionuclide cisternography showed its accumulation in the left ear. Therefore, the diagnosis of cerebrospinal fluid (CSF) leakage was also made in the patient. These findings suggest that traumatic perilymphatic fistula caused the leakage of perilymph from the cochlea, which was made up with a CSF flowing through the cochlear aqueduct. Consequently, the mixture of perilymph and CSF was leaked from the labylinthine window of the patient but her inner ear function was preserved. Therefore, we could diagnose her with perilymphatic oozer, which is characterized by a mild welling-type of perilymph leakage and different from perilymphatic gusher.

Journal

  • Otology Japan

    Otology Japan 22 (3), 274-279, 2012

    Japan Otological Society

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