Assessing the Normal Value of STV-QT

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  • STV-QTの正常値に関する検討

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The measurement of short-term variability of QT interval (STV-QT) is well known for the quantitative evaluation of the instability of the repolarization phase of the heart ventricles and has been, established by clinical and experimental studies. The STV-QT value is suspected to be clinically useful, since the measurement method is non-invasive, measurement time is short (around one minute), and measurement equipment is simple (only ECG recording is required). There have been many reports published concerning the usefulness of STV-QT measurement for discriminating between drug-induced QT prolongation and congenital long QT syndrome, for example, and for prediction of torsade de pointes. In this study, we measured the normal value of STV-QT according to age and sex. STV-QTs were measured in 205 healthy volunteers ranging in age from 20 to 65. The normal STV-QT value ranges 0.7 to 4.7 msec (mean value 2.7msec, standard deviation 1.0msec). No significant differences according to age or sex were observed.

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