Loss of Isosorbide Dinitrate or Nitoglycerin Solution Content in Practice Injection of Precision Continuous Drip Infusion.
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- KAWANO KENJI
- Hospital Pharmacy, Yamanashi Medical University
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- TAKAMATSU SHOJI
- Hospital Pharmacy, Yamanashi Medical University
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- MOCHIZUKI CHIHIRO
- Hospital Pharmacy, Yamanashi Medical University
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- TERAMATSU TSUYOSHI
- Hospital Pharmacy, Yamanashi Medical University
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- NAKAJIMA SHINICHIRO
- Hospital Pharmacy, Yamanashi Medical University
Bibliographic Information
- Other Title
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- 精密持続点滴中の硝酸イソソルビドあるいはニトログリセリン注射液の含量低下
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Description
We investigated the effect of drip conditions on the loss of isosorbide dinitrate (ISDN) or nitroglycerin (GTN) solution contens in practice injection of precision continuous drip infusion. When ISDN or GTN solutions for injection were passed through an intravenous administration tube 100cm in length and 2.1mm inside diameter, at a flow rate of 5.0ml/h, the ISDN or GTN concentrations were reduced to about 30.6% or 10.8% in 60 minutes respectively, and gradually returned to the initial level with time.<BR>It was found that the factors affecting the percentage of remaining ISDN were the length and the inside diameter of the administration tube, the drip rate of the solution, and the tube materials used. Moreover, it was suggested that the amount of ISDN remaining after passage through the administration tube was closely related with the time in which the administration tube was used.
Journal
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- Japanese Journal of Hospital Pharmacy
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Japanese Journal of Hospital Pharmacy 22 (2), 167-172, 1996
Japanese Society of Pharmaceutical Health Care and Sciences
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Details 詳細情報について
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- CRID
- 1390001204774747264
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- NII Article ID
- 110001799565
- 130004299487
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- NII Book ID
- AN00002794
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- ISSN
- 21859477
- 03899098
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- NDL Digital Collections (NII-ELS)
- CiNii Articles
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- Abstract License Flag
- Disallowed